Etiological diagnosis of bloodstream infection: Direct molecular diagnosis from blood
نویسندگان
چکیده
منابع مشابه
Etiological diagnosis of blood-culture-negative endocarditis.
Streptococci in patients who received previous antibiotic treatment and infection of the right heart and specifically on pace makers. The diagnostic strategy of BCNIE starts by serological testing of fastidious agents. At the minimum Coxiella burnetii and Bartonella should be tested. A single serum is sufficient, as endocarditis is a chronic disease associated with high level IgG antibodies. Q ...
متن کاملDNA extraction from primary liquid blood cultures for bloodstream infection diagnosis using whole genome sequencing
PURPOSE Speed of bloodstream infection diagnosis is vital to reduce morbidity and mortality. Whole genome sequencing (WGS) performed directly from liquid blood culture could provide single-assay species and antibiotic susceptibility prediction; however, high inhibitor and human cell/DNA concentrations limit pathogen recovery. We develop a method for the preparation of bacterial DNA for WGS-base...
متن کاملMolecular Diagnosis of Familial Hypercholesterolemia
Abstract Background and objectives: Familial hypercholesterolemia (FH) is an autosomal disorder characterized by increased levels of total cholesterol and low density lipoprotein cholesterol. The FH clinical phenotype has been associated with increased risk of coronary heart disease and premature death. The mutation in LDLR gene in most cases is responsible for FH phenotype. Furthermore, other ...
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ژورنال
عنوان ژورنال: International Journal of Infectious Diseases
سال: 2018
ISSN: 1201-9712
DOI: 10.1016/j.ijid.2018.04.3555